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Rejuran: The Polynucleotide Skin Treatment Now Available in the UK


Over the past few years, Rejuran has become one of the most talked-about regenerative skin treatments in South Korea and Singapore. Known for its ability to improve skin quality from within, it has been widely used by dermatologists and aesthetic doctors across Asia.

More recently, Rejuran has become available in the UK, and I have finally had the opportunity to introduce it into my clinic. Having started working with it, I have been very impressed by its ability to improve skin texture, hydration and overall skin quality.

Unlike traditional dermal fillers that add volume, Rejuran focuses on skin regeneration. It works by stimulating the skin’s natural repair mechanisms, helping to restore healthier, stronger skin over time.

What Is Rejuran?

Rejuran is a polynucleotide-based injectable treatment designed to regenerate and repair the skin.

Polynucleotides are fragments of DNA that support cellular repair and collagen production. In Rejuran, these molecules are derived from highly purified salmon DNA, which is very biocompatible with human skin.

Once injected, polynucleotides help to:

• stimulate collagen production

• improve skin elasticity

• support tissue repair

• reduce inflammation

• strengthen the skin barrier

Rather than simply adding hydration or volume, Rejuran works to improve the health and resilience of the skin itself.

What Makes Rejuran Different From Skin Boosters?

Many patients ask how Rejuran differs from traditional skin boosters, which are typically based on hyaluronic acid.

Skin boosters mainly focus on improving skin hydration.

Rejuran, however, works at a deeper biological level by stimulating tissue repair and collagen production.

For patients with thin, damaged or ageing skin, this regenerative approach can provide longer-term improvements in skin texture and overall skin quality.


The Different Types of Rejuran

Different formulations of Rejuran are designed to treat specific skin concerns.

Rejuran I – Under Eye Rejuvenation

Rejuran I is formulated for the delicate under-eye area.

It can help improve:

• fine lines under the eyes

• crepey skin

• dark circles

• thinning skin

Instead of adding volume like tear trough filler, it focuses on improving the quality and strength of the skin.


Rejuran S – Acne Scars

Rejuran S is designed for acne scars and areas of skin damage.

Its thicker consistency allows it to support tissue repair and collagen production in areas where the skin structure has been weakened.

It can help improve:

• atrophic acne scars

• uneven skin texture

• areas of damaged skin


Rejuran Healer – Overall Skin Rejuvenation

Rejuran Healer is used for overall facial skin rejuvenation.

It is injected across the face to improve:

• skin texture

• elasticity

• enlarged pores

• early signs of ageing


Because the treatment focuses on skin regeneration rather than volume, results appear natural and develop gradually.


What to Expect After Rejuran Treatment

After treatment, small injection marks or bumps may be visible for 24–48 hours. Mild redness or swelling can also occur temporarily.

These effects are normal and usually settle within a few days.

Because Rejuran works by stimulating collagen production and tissue repair, improvements develop gradually over the following weeks.


Who Is a Good Candidate for Rejuran?

Rejuran is ideal for patients looking to improve overall skin quality rather than facial volume.

It may be suitable for concerns such as:

• early signs of ageing

• fine lines and thinning skin

• acne scars and uneven skin texture

• dull or tired-looking skin

• under-eye rejuvenation

The treatment can be suitable for a wide range of skin types and ages.


Rejuran Treatments in Wimbledon

Rejuran treatments are now available at Vanessa Charest Aesthetic in Wimbledon.

If you are interested in improving skin quality, acne scars or under-eye texture, a consultation can help determine whether Rejuran or another regenerative treatment may be suitable for your skin.



Rejuran Treatment FAQ

Is Rejuran the same as filler?

No. Rejuran is not a dermal filler. While fillers add volume to specific areas, Rejuran is a polynucleotide treatment designed to improve skin quality by stimulating collagen production and tissue repair.

How many Rejuran treatments are needed?

Most patients benefit from a course of three treatments, usually spaced three to four weeks apart. Maintenance treatments may be recommended every six to twelve months depending on skin condition.

Is Rejuran good for acne scars?

Yes. Rejuran S is specifically designed to help improve acne scars and uneven skin texture by stimulating collagen production and supporting tissue regeneration.

Can Rejuran be used under the eyes?

Yes. Rejuran I is formulated for the delicate under-eye area and can help improve fine lines, crepey skin and overall skin quality under the eyes.

When will I see results from Rejuran?

Because Rejuran works by stimulating the skin’s natural repair process, results develop gradually over several weeks as collagen production increases.

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